Reaktion #334426

Reaktionsgleichung

triphenylphosphine

3,5-dichlorobenzyl alcohol

1,2-dibromotetrachloroethane

→

3,5-dichlorobenzyl bromide

Ausbeute 100.3%

Lösungsmittel

diethyl ether

diethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwhilst maintaining the reaction temperature below 5° C
2. 2
   workup.ADDITIONWhen the addition
3. 3
   SonstigeThe precipitated solid was removed by filtration
4. 4
   Einengenthe filtrate concentrated by evaporation of the solvent

Vorschrift

A solution of triphenylphosphine (8.1 g) in diethyl ether (100 cm3) was added to a stirred solution of 3,5-dichlorobenzyl alcohol (5 g) and 1,2-dibromotetrachloroethane (9.9 g) in diethyl ether whilst maintaining the reaction temperature below 5° C. When the addition was complete the reaction mixture was allowed to warm to the ambient temperature (ca. 25° C.), and the mixture stirred for a further 2 hours. The precipitated solid was removed by filtration, and the filtrate concentrated by evaporation of the solvent to give 3,5-dichlorobenzyl bromide (6.8 g).

Quelle