Reaktion #334243

Reaktionsgleichung

Triethylamine

2-mercaptobenzo[b]thiophene

bromochloromethane

→

2-(Chloromethylthio)benzo[b]thiophene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Waschenwashed with water
2. 2
   Trocknenthe dried (MgSO4) solution
3. 3
   Sonstigeevaporated
4. 4
   SonstigeThe product was used in Example 30 without further purification

Vorschrift

Triethylamine (20 mmol) was added to a mixture of 2-mercaptobenzo[b]thiophene [see J. Chem. Soc. (C), 2731(1970)] (20 mmol) and bromochloromethane (400 mmol). The mixture was stirred for 30 minutes at room temperature, washed with water and the dried (MgSO4) solution evaporated. Yield 4.08g (95%). 1H-NMR (CDCl3, δ): 4.88 (s, --CH2 --), 7.0-8.0 (m,5H,Ar). The product was used in Example 30 without further purification.

Quelle