Reaktion #330800

Reaktionsgleichung

chlorosulfonic acid

2-nitrophenol

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title compound

Ausbeute 64.0%

4-hydroxy-3-nitrobenzenesulfonyl Chloride

Ausbeute 64.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe reaction was quenched
2. 2
   workup.ADDITIONby pouring it into 100 g of ice
3. 3
   ExtraktionThe reaction was extracted with chloroform (3×)
4. 4
   Waschenwashed with cold water (2×)
5. 5
   Trocknendried over MgSO4
6. 6
   Filtrationfiltered
7. 7
   Einengenconcentrated

Vorschrift

To a solution of chlorosulfonic acid (12.0 mL, 180 mmol) at 0° C. was added 2-nitrophenol (8.35 g, 60.0 mmol) in small portions over 1 h. The reaction was heated to 60° C. for 20 minutes and allowed to stir for 18 h at 25 C. The reaction was quenched by pouring it into 100 g of ice. The reaction was extracted with chloroform (3×), washed with cold water (2×), dried over MgSO4, filtered, and concentrated to give 9.06 g (64%) of the title compound.

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