Reaktion #328574

Reaktionsgleichung

compound ( 1 )

1-Methyl-1,10-phenanthrolinium iodide

sodium hydroxide

→

title compound ( 2 )

Ausbeute 96.4%

1-Methyl-1,10-phenanthroline-2(1H)-one

Ausbeute 96.4%

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe resulting reaction mixture
2. 2
   SonstigeCrude crystals which precipitated out
3. 3
   Filtrationwere filtered out
4. 4
   Sonstigedried
5. 5
   workup.DISSOLUTIONThe resulting crude crystals were dissolved in toluene (1.1 L)
6. 6
   Filtrationbenzene (450 mL), and insoluble matters were filtrated out
7. 7
   SonstigeThe filtrate was evaporated under reduced pressure
8. 8
   Waschenthe resulting residue was washed with isopropyl ether and ethyl acetate
9. 9
   Sonstigedried

Vorschrift

To a stirred aqueous solution of potassium ferricyanide (92.2 g; 280 mmol) (1.12L), compound (1) (37.6 g; 117 mmol) and an aqueous solution of sodium hydroxide (69.3 g; 1.73 mol) (200 mL) were alternately added in an ice bath (inner temperature of 10 to 15° C.) over 20 minutes. The resulting reaction mixture was stirred at room temperature for 3 hours. Crude crystals which precipitated out were filtered out and dried. The resulting crude crystals were dissolved in toluene (1.1 L) and benzene (450 mL), and insoluble matters were filtrated out. The filtrate was evaporated under reduced pressure, and the resulting residue was washed with isopropyl ether and ethyl acetate, and then dried to give 23.7 g (yield: 75%) of the title compound (2).

Quelle