Reaktion #327633

Reaktionsgleichung

product

tert-butyl (7R,8aS)-7-{[5-(prop-1-en-2-yl)pyrazin-2-yl]oxy}hexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate

HCl

→

title compound

(7R,8aS)-7-{[5-(prop-1-en-2-yl)pyrazin-2-yl]oxy}octahydropyrrolo[1,2-a]-pyrazine hydrochloride

Lösungsmittel

1,4-dioxane

1,4-dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenthe mixture was then concentrated

Vorschrift

To a solution of the product from Example 202B (100 mg, 0.277 mmol) in 1,4-dioxane (1 mL) was added 4 N HCl in 1,4-dioxane (1 mL, 4.00 mmol). The resulting mixture was stirred at ambient temperature for 3 hours, and the mixture was then concentrated to give the title compound as an off-white solid (82 mg, quantitative).

Quelle