Reaktion #325227

Reaktionsgleichung

4-chloro-5-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine

NH3 MeOH

→

5-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeReaction
2. 2
   Einengenwas concentrated in vacuo
3. 3
   Sonstigeto give a brown/off-white solid

Vorschrift

4-chloro-5-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine (90 mg, 0.31 mmol) was taken up in 7N NH3/MeOH and heated in a sealed tube at 110° C. overnight. Reaction was concentrated in vacuo to give a brown/off-white solid.

Quelle