Reaktion #324993

Reaktionsgleichung

1-benzyloxy-4-(3,3,5,5-tetramethyl-cyclohex-1-enyl)-benzene

→

title compound

Ausbeute 96.6%

4-(3,3,5,5-Tetramethyl-cyclohexyl)-phenol

Ausbeute 96.6%

Lösungsmittel

MeOH

EtOAc

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeprepared by a substantially similar procedure to that of Step 1 of Example 18
2. 2
   FiltrationThe reaction mixture was filtered through celite
3. 3
   EinengenThe filtrate was concentrated

Vorschrift

To 10% Pd/C (0.17 g) under N2 was added 1-benzyloxy-4-(3,3,5,5-tetramethyl-cyclohex-1-enyl)-benzene (1.7 g, 5.3 mmol), prepared by a substantially similar procedure to that of Step 1 of Example 18, in MeOH (15 mL) and EtOAc (15 mL). This mixture was stirred under H2 (1 atm) overnight. The reaction mixture was filtered through celite. The filtrate was concentrated to give the title compound as a white solid (1.19 g).

Quelle