Reaktion #324357

ord-d462e560295c43619fd1051cdff138e4

Reaktionsgleichung

c1ccc(NCc2cccnc2)cc1
3-anilinomethylpyridine
c1ccc(CNc2ccccc2)cc1
N-benzylaniline
O=Cc1cccnc1
nicotin-aldehyde
→
c1ccc(Nc2ccccn2)cc1
Anilino-Pyridine

Edukte

c1ccc(NCc2cccnc2)cc1
3-anilinomethylpyridine
c1ccc(CNc2ccccc2)cc1
N-benzylaniline
O=Cc1cccnc1
nicotin-aldehyde

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The synthesis of 3-anilinomethylpyridine precursors should proceed similar to the synthesis of N-benzylaniline described in Example 7 except with nicotin-aldehyde as the reagent:

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08642014B2uspto-grants-2014_02