Reaktion #323678

ord-d44b5d8c9247487fb9d5673496032423

Reaktionsgleichung

CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)O
3-hexadecanoyloxyoctadecanoic acid
NCCC(=O)N[C@@H](CC(=O)O)C(=O)O
N-(β-alanyl)-L-aspartic acid
→
CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)NCCC(=O)N[C@@H](CC(=O)O)C(=O)O
N-[N-(3-hexadecanoyloxyoctadecanoyl)-β-alanyl]-L-aspartic acid
Ausbeute 24.8%

Edukte

CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)O
3-hexadecanoyloxyoctadecanoic acid
—
( 5 )
NCCC(=O)N[C@@H](CC(=O)O)C(=O)O
N-(β-alanyl)-L-aspartic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigeprepared by the method

Vorschrift

Starting from 3-hexadecanoyloxyoctadecanoic acid (150 mg) prepared by the method described in Preparation A-2 (5) and N-(β-alanyl)-L-aspartic acid (150 mg), N-[N-(3-hexadecanoyloxyoctadecanoyl)-β-alanyl]-L-aspartic acid (50 mg) was obtained as powder according to a similar manner to that of Example 2.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04643990uspto-grants-1987_02