Reaktion #323672

ord-0531239087444516ad3c28429b7494b8

Reaktionsgleichung

CCCCCCCCC=CCCCCCCCC(=O)OC(CCCCCCCC=CCCCCCCCC)CC(=O)N[C@H](C(=O)O)C(C)C
N-[3-(9-octadecenoyloxy)-11-eicosenoyl]-L-valine
N[C@@H](CCC(=O)O)C(=O)O
L-glutamic acid
→
CCCCCCCCC=CCCCCCCCC(=O)OC(CCCCCCCC=CCCCCCCCC)CC(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)C(C)C
N-[N-[3-(9-octadecenoyloxy)-11-eicosenoyl]-L-valyl]-L-glutamic acid
Ausbeute 31.2%

Edukte

CCCCCCCCC=CCCCCCCCC(=O)OC(CCCCCCCC=CCCCCCCCC)CC(=O)N[C@H](C(=O)O)C(C)C
N-[3-(9-octadecenoyloxy)-11-eicosenoyl]-L-valine
N[C@@H](CCC(=O)O)C(=O)O
L-glutamic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Starting from N-[3-(9-octadecenoyloxy)-11-eicosenoyl]-L-valine (2.7 g) and L-glutamic acid (2.2 g), N-[N-[3-(9-octadecenoyloxy)-11-eicosenoyl]-L-valyl]-L-glutamic acid (1.0 g) was obtained as powder according to a similar manner to that of Example 2.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04643990uspto-grants-1987_02