Reaktion #323525

Reaktionsgleichung

7-(1-ethoxycarbonylethyl)oxy-3-phenyl-4H-1-benzopyran-4-one

dioxane

hydrochloric acid

→

7-(1-hydroxycarbonylethyl)oxy-3-phenyl-4H-1-benzopyran-4-one

Ausbeute 93.2%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for 4 hours
2. 2
   FiltrationThe resulting crystalline precipitate was collected by filtration
3. 3
   Sonstigerecrystallized from ethanol

Vorschrift

A mixture of 20 g of 7-(1-ethoxycarbonylethyl)oxy-3-phenyl-4H-1-benzopyran-4-one, 200 ml of dioxane, 70 ml of hydrochloric acid and 150 ml of water was refluxed for 4 hours and poured into ice water. The resulting crystalline precipitate was collected by filtration and recrystallized from ethanol to give 17.1 g of 7-(1-hydroxycarbonylethyl)oxy-3-phenyl-4H-1-benzopyran-4-one as white crystals. m.p. 223° C.

Quelle