Reaktion #323493

ord-793435134d974c9c87bc817d18048194

Reaktionsgleichung

CN(CCc1ccc(O)c(O)c1)C(=O)OCc1ccccc1
N-methyl-N-carbobenzoxy-dopamine
O=C(NCCc1ccc(O)c(O)c1)OCc1ccccc1
N-carbobenzoxy-dopamine
→
O=C(NCCC1=CC(O)(C(=O)c2cccnc2)C(O)(C(=O)c2cccnc2)C=C1)OCc1ccccc1
3,4-dinicotinoyl-N-carbobenzoxy-dopamine

Edukte

CN(CCc1ccc(O)c(O)c1)C(=O)OCc1ccccc1
N-methyl-N-carbobenzoxy-dopamine
O=C(NCCc1ccc(O)c(O)c1)OCc1ccccc1
N-carbobenzoxy-dopamine

Reagenzien

Keine

Lösungsmittel

c1ccccc1
benzene

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

By working as described in Example 1, but replacing the N-methyl-N-carbobenzoxy-dopamine with an equivalent amount of N-carbobenzoxy-dopamine, 3,4-dinicotinoyl-N-carbobenzoxy-dopamine is obtained (m.p. 86°-90° C., from benzene).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04644004uspto-grants-1987_02