Reaktion #322391

ord-95cb0e4d69ad4219994ad817ae6e22e3

Reaktionsgleichung

C(=NC1CCCCC1)=NC1CCCCC1
dicyclohexylcarbodiimide
C[C@@H]1C[C@@H]2O[C@@H]2/C=C\C=C\C(=O)Cc2c(Cl)c(O)cc(O)c2C(=O)O1
radicicol
CCCCCCCCCCCCCCCC(=O)O
palmitic acid
→
CN(C)c1ccccn1
dimethylaminopyridine

Edukte

C(=NC1CCCCC1)=NC1CCCCC1
dicyclohexylcarbodiimide
C[C@@H]1C[C@@H]2O[C@@H]2/C=C\C=C\C(=O)Cc2c(Cl)c(O)cc(O)c2C(=O)O1
radicicol
CCCCCCCCCCCCCCCC(=O)O
palmitic acid

Reagenzien

Keine

Lösungsmittel

C1CCOC1
tetrahydrofuran

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following a procedure similar to that described in Example 12, but using 364 mg of radicicol, 384 mg of palmitic acid, 15 ml of dry tetrahydrofuran, 309 mg of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 62 mg of the title compound were obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05597846uspto-grants-1997_01