Reaktion #321571

ord-2e1a80b3724f4af0a24c693dc6673ddd

Reaktionsgleichung

CN(C)C=O
DMF
O=S(=O)(Cl)Cl
sulfurylchloride
CCc1cc2cc(C)ccc2s1
2-ethyl-5-methylbenzo[b]thiophene
→
CCc1sc2ccc(C)cc2c1S(=O)(=O)Cl
2-ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride

Edukte

—
ethyl acetate hexanes
CN(C)C=O
DMF
O=S(=O)(Cl)Cl
sulfurylchloride
CCc1cc2cc(C)ccc2s1
2-ethyl-5-methylbenzo[b]thiophene
—
orange solid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigeyielded

Vorschrift

2-ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride was prepared in the same manner as described in Example 40B. Reaction of DMF (6.5 mmoles, 0.50 ml), sulfurylchloride (5.5 mmoles, 0.44 ml) and 2-ethyl-5-methylbenzo[b]thiophene (3.2 mmoles, 0.57 g) yielded, after flash chromatography, using 2% ethyl acetate/hexanes, 0.58 g (66%) of an orange solid.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05594021uspto-grants-1997_01