Reaktion #321528

Reaktionsgleichung

piperonal

benzo[b]thiophene

t-BuLi

→

α-(2-Benzo[b]thienyl)-3,4-(methylenedioxy)benzyl alcohol

Lösungsmittel

THF

Reaktionsbedingungen

Vorschrift

α-(2-Benzo[b]thienyl)-3,4-(methylenedioxy)benzyl alcohol was prepared by the method of Example 40A using benzo[b]thiophene (7.5 mmoles, 1.0 g), t-BuLi (1.7M, 9.7 mmoles, 5.7 ml), piperonal (8.9 mmoles, 1.0 g) and THF (20 ml). Flash chromatography (20% ethyl acetate/hexanes) provided 1.6 g (74%) of a yellow solid.

Quelle