Reaktion #320776

ord-08e15ca19ca441b5b157ec7cb0076105

Reaktionsgleichung

OB(O)c1ccc(Cl)cc1
4-chlorophenylboronic acid
Brc1cccc(Br)c1
1,3-dibromobenzene
O=C([O-])[O-].[Na+].[Na+]
sodium carbonate
Clc1ccc(-c2cccc(Br)c2)cc1
3-(4-chlorophenyl)phenyl bromide

Lösungsmittel

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThis compound is prepared in a manner analogous to that of Step D of Example 4

Vorschrift

This compound is prepared in a manner analogous to that of Step D of Example 4, using 6.9 grams (0.044 mole) of 4-chlorophenylboronic acid (commercially available), 25.0 grams (0.100 mole) of 1,3-dibromobenzene, 0.2 gram (catalyst) of tetrakis(triphenylphosphine)palladium(0), 75 mL of aqueous 2M sodium carbonate, and 75 mL of toluene, yielding 3-(4-chlorophenyl)phenyl bromide.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05593998uspto-grants-1997_01