Reaktion #319692

ord-ecd33c8f4e6f4c3a97da7f438e9ae949

Reaktionsgleichung

N=C(N)NCCCC(N)C(=O)O
DL-arginine
O=C1O[C@H]([C@@H](O)CO)C(O)=C1O
ascorbic acid
N=C(N)NCCC[C@H](N)C(=O)O
L-Arg
N=C(N)NCCC[C@H](N)C(=O)O
arginine
→
NCCC[C@H](N)C(=O)O
ornithine

Edukte

—
·
N=C(N)NCCCC(N)C(=O)O
DL-arginine
O=C1O[C@H]([C@@H](O)CO)C(O)=C1O
ascorbic acid
N=C(N)NCCC[C@H](N)C(=O)O
L-Arg
N=C(N)NCCC[C@H](N)C(=O)O
arginine

Reagenzien

O.O=S(=O)([O-])[O-].[Mn+2]
MnSO4.H2O

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

100 ml of a 1.25 molar, racemic solution of DL-arginine are mixed with 5·10-4 mol/l MnSO4.H2O, 2.5·10-4 mol/1 ascorbic acid and 14.0 mg L-arginase (=10000 U/(l·mol L-Arg)). After 22 hours, the conversion was 50% of the original amount of arginine and a corresponding amount of ornithine had been produced.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05591613uspto-grants-1997_01