Reaktion #318449

Reaktionsgleichung

12-cyclohexyldodecanol

epichlorohydrin

sodium hydroxide

→

captioned compound

Ausbeute 71.2%

1,2-Epoxy-3-(12-cyclohexyldodecyloxy)propane

Ausbeute 71.2%

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe resulting reaction mixture
2. 2
   Waschenis then washed with water
3. 3
   Sonstigedried
4. 4
   Einengenconcentrated
5. 5
   Sonstigeto leave a residue which in turn
6. 6
   Sonstigeis purified by silica gel chromatography

Vorschrift

A mixture containing 26.5 g of 12-cyclohexyldodecanol, 27.4 g of epichlorohydrin, 52.6 g of a 50% aqueous sodium hydroxide solution, 2.0 g of cetyltrimethylammonium chloride and 300 ml of toluene is stirred at 60° C. for 24 hours. The resulting reaction mixture is then washed with water, dried and concentrated to leave a residue which in turn is purified by silica gel chromatography to obtain 22.8 g of the captioned compound as a colorless oily substance.

Quelle