Reaktion #312409

Reaktionsgleichung

triethylamine

2,2-dimethyl thiazolidine

benzene

dibromoacetyl chloride

→

2,2-dimethyl-3-dibromoacetyl thiazolidine

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONTo a mixture of 3.5 g
2. 2
   workup.ADDITIONwas added 3.1 g
3. 3
   Temperaturcontinued cooling
4. 4
   SonstigeWhen reaction
5. 5
   Sonstigethe benzene layer separated
6. 6
   Trocknendried over magnesium sulfate
7. 7
   Sonstigethe benzene removed under vacuum

Vorschrift

To a mixture of 3.5 g. of 2,2-dimethyl thiazolidine, 50 ml. of benzene and 7.1 g. of dibromoacetyl chloride mixed in an ice bath was added 3.1 g. of triethylamine dropwise with stirring and continued cooling. When reaction was complete, the mixture was poured into water and the benzene layer separated, dried over magnesium sulfate and the benzene removed under vacuum. Yield was 8.5 g. of a dark oil.

Quelle