Reaktion #312137
ord-d650cda4d36044df91bdf1a415ecc60b
Reaktionsgleichung
6-bromohexanoic acid methyl ester
potassium cyanate
methanol
→
6-methoxycarbonylaminohexanoic acid methyl ester
Ausbeute 77.0%
Reagenzien
Keine
Lösungsmittel
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
The reaction of 10.45 grams of 6-bromohexanoic acid methyl ester with 6.08 grams of potassium cyanate and 2.7 grams of methanol in 50 ml DMF following the procedure of Example 1 gave 7.82 grams (76.9%) of 6-methoxycarbonylaminohexanoic acid methyl ester having a boiling point of 104° C./0.0013 mbar.