Reaktion #311652

Reaktionsgleichung

Boron trifluoride

palmitic acid

2-methylhydroquinone

sodium acetate

→

2-methyl-5-hexadecanoylhydroquinone

Lösungsmittel

methylene chloride

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture was refluxed for another hour
2. 2
   SonstigeAfter 45 min the solution in methylene chloride was separated
3. 3
   Sonstigeevaporated
4. 4
   Filtrationfiltered with suction
5. 5
   Sonstigerecrystallized from n-chlorobutane

Vorschrift

Boron trifluoride was introduced with vigorous refluxing until saturation into a mixture of 27.2 g of palmitic acid, 13.7 g of 2-methylhydroquinone and 45 ml of methylene chloride. After standing overnight the mixture was refluxed for another hour and then decomposed with stirring in a solution of 25 g of sodium acetate in 220 ml of water. After 45 min the solution in methylene chloride was separated and evaporated. The residue was stirred with methanol, filtered with suction and recrystallized from n-chlorobutane.

Quelle