Reaktion #311

Reaktionsgleichung

CN1Cc2ccc(Cl)nc2O[C@

Cc1ncn(-c2ccc(N)cc2)

→

Cc1ncn(-c2ccc(Nc3ccc

Lösungsmittel

COCCOC

Reaktionsbedingungen

Vorschrift

A solution of (R)-8-chloro-4-methyl-2-phenyl-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine (5.00 mg, 0.02 mmol) and 4-(3-methyl-1H-1,2,4-triazol-1-yl)aniline (3.17 mg, 0.02 mmol) in DME (.5 mL) was added via a syringe to a capped microwave vial containing PALLADIUM(II) ACETATE (0.409 mg, 1.82 µmol), XANTPHOS (1.053 mg, 1.82 µmol) and CESIUM CARBONATE (8.89 mg, 0.03 mmol) under an argon atmosphere. The resulting mixture was heated to 100°C in a microwavwe apparatus for 1 h and analyzed by LCMS. No product.

Quelle