Reaktion #310707

Reaktionsgleichung

acryloyl chloride

alanine ethyl ester hydrochloride

sodium carbonate

→

N-acryloylalanine ethyl ester

Lösungsmittel

benzene

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe reaction mixture is then refluxed for 1 hour
2. 2
   Filtrationfiltered
3. 3
   Einengenthe filtrate concentrated

Vorschrift

To 0.5 moles of alanine ethyl ester hydrochloride in 500 ml. of benzene is added 0.5 moles of acryloyl chloride. To this stirred mixture is added portionwise 0.6 moles of anhydrous sodium carbonate. The reaction mixture is then refluxed for 1 hour, stirred an additional 2 hours, filtered, and the filtrate concentrated to give N-acryloylalanine ethyl ester.

Quelle