Reaktion #310282
ord-2f8b4e10c4a54e87bfcc00d9315494c1
Reaktionsgleichung
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
According to the same procedure as in Example 1, 1-(1-methoxycarbonyl-2-phenylethyl)-3-benzyloxy-4-phenylazetidin-2-one (1.0 g.) was subjected to hydrogenolysis at 50° C. in methanol (50 ml.) under a hydrogen pressure of one atmosphere in the presence of a 10% Pd-C (255 mg.). The reaction was completed in 48 hours. The same after-treatment as in Example 1 was followed to give methyl ester of α-hydroxy-β-phenylpropionylphenylalanine (784 mg., yield: 100%), which was an oil.