Reaktion #308596

Reaktionsgleichung

4-bromobenzene sulfonyl chloride

3-amino-2-methylbenzoic acid

→

title compound

3-(4-Bromophenylsulfonamido)-2-methylbenzoic acid

Lösungsmittel

pyridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe title compound was prepared
2. 2
   SonstigeThe title compound was precipitated
3. 3
   Sonstigeon partition of the reaction mixture between dilute HCl and DCM
4. 4
   FiltrationThe precipitate was collected by filtration
5. 5
   workup.DISSOLUTIONdissolved in ethyl acetate
6. 6
   Sonstigedried
7. 7
   SonstigeEvaporation of the solvent

Vorschrift

The title compound was prepared using a method analogous to Method A, using 4-bromobenzene sulfonyl chloride, 3-amino-2-methylbenzoic acid, and a large excess of pyridine. The title compound was precipitated on partition of the reaction mixture between dilute HCl and DCM. The precipitate was collected by filtration, dissolved in ethyl acetate and dried. Evaporation of the solvent gave the title compound as a pale brown solid.

Quelle