Reaktion #3063

Reaktionsgleichung

3-iodo-4-methylbenzoic acid

TsCl

methylamine hydrochloride

→

N-methyl-(3-iodo-4-methylphenyl)carboxamide

Reaktionsbedingungen

Vorschrift

A solution of 1.0 mmol of 3-iodo-4-methylbenzoic acid, 1.2 mmol of TsCl, and 25 mmol of Py was stirred for 3 h and then 5 mmol of methylamine hydrochloride was added and stirring continued for 5 h. Chromatography provided N-methyl-(3-iodo-4-methylphenyl)carboxamide.

Quelle