Reaktion #305422

ord-65c9d0e14e114f47a07e1f45f656d75b

Reaktionsgleichung

CC(=O)OCC[N+](C)(C)C
acetylcholine
NCCc1c[nH]c2ccc(O)cc12
serotonin
→
CC(=O)OCC[N+](C)(C)C.NCCc1c[nH]c2ccc(O)cc12
Acetylcholine Serotonin

Edukte

CC(=O)OCC[N+](C)(C)C
acetylcholine
NCCc1c[nH]c2ccc(O)cc12
serotonin

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Microdialysis studies (resting or challenging conditions) in freely moving, male Sprague Dawley rats (Janvier, 295-315 g, n=5-8/treatment group) were performed using stereotactically instrumented microdialysis probes (CMA/12-14-2): mPFC, hippocampus. Aliquots of the same microdialysate fractions (6 before, and 9-12 after compound administration) were analyzed either for acetylcholine or for serotonin by HPLC and electrochemical detection.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08198331B2uspto-grants-2012_06