Reaktion #305320

Reaktionsgleichung

(2-(1-(4-Fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropyl)methanamine

2,2,2-trifluoroethanesulfonyl chloride

→

2,2,2-trifluoro-N-((2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropyl)methyl)ethanesulfonamide

Ausbeute 86.0%

Reaktionsbedingungen

Vorschrift

(2-(1-(4-Fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropyl)methanamine (71 mg, 0.15 mmol) was coupled with 2,2,2-trifluoroethanesulfonyl chloride (50 mg, 0.5 mmol) using General Coupling Method B to give 60 mg (86% yield) of 2,2,2-trifluoro-N-((2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropyl)methyl)ethanesulfonamide. MS found: (M+H)+=504.

Quelle