Reaktion #304888

Reaktionsgleichung

Hydrazine dihydrochloride

3,4-dimethylfuran-2,5-dione

→

title compound

Ausbeute 62.5%

4,5-Dimethyl-1,2-dihydropyridazine-3,6-dione

Ausbeute 62.5%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThen the mixture was heated
2. 2
   Temperaturto reflux for 3 h
3. 3
   SonstigeSubsequently, the precipitate formed
4. 4
   Filtrationwas filtered off with suction
5. 5
   Waschenwashed with water
6. 6
   Sonstigedried
7. 7
   Filtrationfiltered off with suction
8. 8
   Sonstigedried

Vorschrift

Hydrazine dihydrochloride (83.6 g) was dissolved in water (20 ml) and heated to 100° C., and 3,4-dimethylfuran-2,5-dione (100.4 g) was introduced while stirring. Then the mixture was heated to reflux for 3 h. Subsequently, the precipitate formed was filtered off with suction, washed with water and dried. The residue was suspended in EA (2 l), filtered off with suction and dried. 69.7 g of the title compound were obtained. LC-MS rt: 0.19 min[M+H]+: 141.1 (met. b)

Quelle