Reaktion #2995

Reaktionsgleichung

(Z)-1-(3-nitro-4-methylphenyl)-2-(3,4,5-trimethoxyphenyl) ethene

→

intended compound

Ausbeute 49.1%

(Z)-1-(3-amino-4-methylphenyl)-2-(3,4,5-trimethoxyphenyl)ethene

Ausbeute 49.1%

Lösungsmittel

acetic acid

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe reaction liquid
2. 2
   Filtrationwas filtered
3. 3
   Einengenconcentrated
4. 4
   Sonstigepurified by silica gel column chromatography (dichloromethane:hexane=2.1 by volume)

Vorschrift

65 mg of (Z)-1-(3-nitro-4-methylphenyl)-2-(3,4,5-trimethoxyphenyl) ethene were dissolved in 4 ml of acetic acid and 4 ml of dichloromethane, and 300 mg of zinc were added thereto and stirred for one hour. The reaction liquid was filtered, concentrated and purified by silica gel column chromatography (dichloromethane:hexane=2.1 by volume) to obtain 29 mg of the intended compound. The yield was 46.5%.

Quelle