Reaktion #2937

ord-51c44092234a4bbebe6940b7ac132c46

Reaktionsgleichung

CCOC(=O)CC(C)=O
ethyl acetoacetate
CCNCC
diethylamine
→
CCN(CC)C(=O)CC(C)=O
title compound
Ausbeute 65.7%
CCN(CC)C(=O)CC(C)=O
N,N Diethyl-3-oxobutyramide
Ausbeute 65.7%

Edukte

CCOC(=O)CC(C)=O
ethyl acetoacetate
CCNCC
diethylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    workup.DISTILLATIONThe crude mixture was distilled at 115°-120° C./9 mmHg

Vorschrift

40 g (0.31 mol) of ethyl acetoacetate and 24 g (0.33 mol) of diethylamine were stirred in a Parr apparatus at 150° C. for 10'. The crude mixture was distilled at 115°-120° C./9 mmHg, to give 32 g of the title compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05731322uspto-grants-1998_03