Reaktion #2837

Reaktionsgleichung

(-)-(R)-2-methoxypropanol

p-toluenesulphonic acid chloride

→

(+)-(R)-2-methoxypropyl-p-toluenesulphonate

Lösungsmittel

pyridine

Reaktionsbedingungen

Vorschrift

By reacting (-)-(R)-2-methoxypropanol with p-toluenesulphonic acid chloride in pyridine analogously to R. S. Tipson [J. Org. Chem. 9 (1944) 235] the (+)-(R)-2-methoxypropyl-p-toluenesulphonate is obtained in the form of a yellowish oil with a specific rotation of [α]D25 =+3.7° (c=100) and analogously, from (+)-(S)-2-methoxy-propanol, the corresponding (-)-(S)-2-methoxypropyl-p-toluenesulphonate is obtained with a rotation of [α]D25 =-3.7° (c=100).

Quelle