Reaktion #2532

ord-d6f0bef2d28347ca947ceb2e3c17a182

Reaktionsgleichung

COc1ccc(N)cc1
p-anisidine
COc1cc(C(=O)O)ccc1[N+](=O)[O-]
3-methoxy-4-nitrobenzoic acid
→
COc1ccc(NC(=O)c2ccc([N+](=O)[O-])c(OC)c2)cc1
title compound
Ausbeute 92.7%
COc1ccc(NC(=O)c2ccc([N+](=O)[O-])c(OC)c2)cc1
3-Methoxy-4-nitro-N-(4-methoxyphenyl)benzamide
Ausbeute 92.7%

Edukte

COc1ccc(N)cc1
p-anisidine
COc1cc(C(=O)O)ccc1[N+](=O)[O-]
3-methoxy-4-nitrobenzoic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Using p-anisidine (738 mg, 6.0 mmol) and 3-methoxy-4-nitrobenzoic acid (986 mg, 5.0 mmol), the procedure of Reference Example 16 was repeated to obtain 1.40 g (92.7%) of the title compound in the form of colorless powder.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05728835uspto-grants-1998_03