Reaktion #2507899

ord-7b97580176634f18a5e29dea9a5d8560

Reaktionsgleichung

COc1ccc(NC(=O)c2cc(Br)c[nH]2)cc1OC
product
COc1ccc(NC(=O)c2cc(Br)c[nH]2)cc1OC
4-bromo-N-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxamide
BrCCBr
1,2-dibromoethane
COc1ccc(N2CCn3cc(Br)cc3C2=O)cc1OC
title compound
COc1ccc(N2CCn3cc(Br)cc3C2=O)cc1OC
7-bromo-2-(3,4-dimethoxyphenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following the procedure described in Example 1 step D, the product of step A (140 mg) was alkylated with 1,2-dibromoethane to yield 143 mg of the title compound. MS (ESI) 351, 353 (M+H)+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07956049B2uspto-grants-2011_06