Reaktion #2507898
ord-4aa10a2d16344848a5f47bef1e98ae62
Reaktionsgleichung
(R)-1-(4-Amino-2-methoxyphenyl)pyrrolidin-3-ol
4-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid
→
title compound
(R)-4-(4-chlorophenyl)-N-(4-(3-hydroxypyrrolidin-1-yl)-3-methoxyphenyl)-1H-pyrrole-2-carboxamide
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
(R)-1-(4-Amino-2-methoxyphenyl)pyrrolidin-3-ol, preparation described in PCT application WO 2005/042541, was converted to the title compound (48 mg) by acylation with 4-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid (30 mg) following the procedure described in step C of Example 1. MS (ESI) 412 (M+H)+.