Reaktion #2507892

ord-1095ba4d631141fdbbad0c9c69f54e05

Reaktionsgleichung

Nc1ccc(OCCN2CCCC2)c(Cl)c1
3-Chloro-4-(2-(pyrrolidin-1-yl)ethoxy)benzenamine
O=C(O)c1cc(-c2ccc(Cl)cc2)c[nH]1
4-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid
O=C(Nc1ccc(OCCN2CCCC2)c(Cl)c1)c1cc(-c2ccc(Cl)cc2)c[nH]1
title compound
O=C(Nc1ccc(OCCN2CCCC2)c(Cl)c1)c1cc(-c2ccc(Cl)cc2)c[nH]1
N-(3-chloro-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-4-(4-chlorophenyl)-1H-pyrrole-2-carboxamide

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

3-Chloro-4-(2-(pyrrolidin-1-yl)ethoxy)benzenamine was converted to the title compound (20 mg) by acylation with 4-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid following the procedure described in step C of Example 1. MS (ESI) 444 (M+H)+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07956049B2uspto-grants-2011_06