Reaktion #2507889

ord-35d1fae9738f4757a90a16a2e470dc67

Reaktionsgleichung

COc1ccc(N)cc1OCCN1CCCC1
4-methoxy-3-(2-(pyrrolidin-1-yl)ethoxy)benzenamine
O=C(O)c1cc(-c2ccc(Cl)cc2)c[nH]1
4-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid
COc1ccc(NC(=O)c2cc(-c3ccc(Cl)cc3)c[nH]2)cc1OCCN1CCCC1
title compound
Ausbeute 74.0%
COc1ccc(NC(=O)c2cc(-c3ccc(Cl)cc3)c[nH]2)cc1OCCN1CCCC1
4-(4-chlorophenyl)-N-(4-methoxy-3-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1H-pyrrole-2-carboxamide
Ausbeute 74.0%

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Acylation of 4-methoxy-3-(2-(pyrrolidin-1-yl)ethoxy)benzenamine from step A with 4-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid to generate the title compound in 74% yield was achieved via the procedure described in step C of Example 1. MS (ESI) 440 (M+H)+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07956049B2uspto-grants-2011_06