Reaktion #2507879

ord-7a737016fe0a4254801471fca8dcc8b3

Reaktionsgleichung

Nc1ccc(OCCN2CCCC2)nc1
5-Amino-2-((pyrrolidin-1-yl)ethoxy)pyridine
O=C(O)c1cc(-c2ccc(Cl)cc2)c[nH]1
4-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid
O=C(Nc1ccc(OCCN2CCCC2)nc1)c1cc(-c2ccc(Cl)cc2)c[nH]1
title compound
O=C(Nc1ccc(OCCN2CCCC2)nc1)c1cc(-c2ccc(Cl)cc2)c[nH]1
4-(4-chlorophenyl)-N-(6-(2-(pyrrolidin-1-yl)ethoxy)pyridin-3-yl)-1H-pyrrole-2-carboxamide

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

5-Amino-2-((pyrrolidin-1-yl)ethoxy)pyridine was converted to the title compound (18 mg) by acylation with 4-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid (21 mg) following the procedure described in step C of Example 1. MS (ESI) 411 (M+H)+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07956049B2uspto-grants-2011_06