Reaktion #2507869

ord-abe1ebf31c0e4e949b6c343e58b46774

Reaktionsgleichung

CCC(CC)n1c(O)nc2ncc(Br)nc21
6-bromo-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2-ol
C[S-].[Na+]
sodium thiomethoxide
CCC(CC)n1c(O)nc2ncc(SC)nc21
title compound
CCC(CC)n1c(O)nc2ncc(SC)nc21
6-(methylthio)-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2-ol

Lösungsmittel

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared by reacting 6-bromo-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2-ol (1.0 equiv), sodium thiomethoxide (1.4 equiv), and N-methylpyrrolidone (5.9 volume equivalents) in a manner analagous to Example 1(c). LCMS m/z (APCI)=253.0 (M+H).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07956056B2uspto-grants-2011_06