Reaktion #2503783

Reaktionsgleichung

1-(5-Methoxymethoxy-3-pyridyl)-homopiperazine

hydrochloric acid

→

1-(5-Hydroxy-3-pyridyl)-homopiperazine hydrochloric acid salt

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe excess of hydrochloric acid was evaporated
2. 2
   SonstigeA crystaline compound was obtained
3. 3
   Sonstigeby triturating with a mixture of 5% methanol and ether

Vorschrift

1-(5-Methoxymethoxy-3-pyridyl)-homopiperazine (8.5 g, 35.9 mmol) was stirred in hydrochloric acid (4 M, 100 ml) at room temperature for 1 h. The excess of hydrochloric acid was evaporated. A crystaline compound was obtained by triturating with a mixture of 5% methanol and ether. Yield 9.56 g, 100%. Mp 290-300° C.

Quelle