Reaktion #2503541

Reaktionsgleichung

hydrochloric acid

Oxygen

4-(2-(2-pentyloxyfluorene-7-yl)ethyl)phenyl acetate

potassium hydroxide

→

4-(2-(2-pentyloxyfluorenone-7-yl)ethyl)phenyl acetate

Lösungsmittel

2-butanone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwhile refluxing
2. 2
   Temperaturby heating
3. 3
   Extraktionthe product was extracted with chloroform
4. 4
   Trocknento dry the chloroform layer on anhydrous magnesium sulfate
5. 5
   SonstigeA residue obtained
6. 6
   workup.DISTILLATIONby distilling the solvent off from this organic layer
7. 7
   Sonstigewas purified by means of column chromatography (silica gel, eluting solvent: toluene)

Vorschrift

Oxygen was blown into a solution comprising 4-(2-(2-pentyloxyfluorene-7-yl)ethyl)phenyl acetate (4.2 g), powdery potassium hydroxide (1.0 g) and 2-butanone (80 mL) for one hour while refluxing by heating, and the solution was further stirred at a room temperature for one hour. A hydrochloric acid aqueous solution was added thereto, and then the product was extracted with chloroform to dry the chloroform layer on anhydrous magnesium sulfate. A residue obtained by distilling the solvent off from this organic layer was purified by means of column chromatography (silica gel, eluting solvent: toluene) to obtain 4-(2-(2-pentyloxyfluorenone-7-yl)ethyl)phenyl acetate (2.3 g).

Quelle