Reaktion #2486387

ord-bd8a1e0758fe48f3a5d33959df1f19a2

Reaktionsgleichung

CCCOc1cccc(-c2ncc(Br)cn2)c1
5-Bromo-2-(3-propoxyphenyl)pyrimidine
OB(O)c1ccc(OCc2ccccc2)cc1
4-benzyloxybenzeneboronic acid
→
CCCOc1cccc(-c2ncc(-c3ccc(OCc4ccccc4)cc3)cn2)c1
5-(4-benzyloxyphenyl)-2-(3-propoxyphenyl)pyrimidine

Edukte

CCCOc1cccc(-c2ncc(Br)cn2)c1
5-Bromo-2-(3-propoxyphenyl)pyrimidine
OB(O)c1ccc(OCc2ccccc2)cc1
4-benzyloxybenzeneboronic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

5-Bromo-2-(3-propoxyphenyl)pyrimidine and 4-benzyloxybenzeneboronic acid (preparation analogous to 3-benzyloxybenzeneboronic acid) are reacted analogously to Example 1 to give 5-(4-benzyloxyphenyl)-2-(3-propoxyphenyl)pyrimidine. ##STR41##

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05447656uspto-grants-1995_09