Reaktion #2485643

Reaktionsgleichung

5-Chloro-3-[4-(3-bromopropoxy)benzoyl]-2-phenylbenzofuran

diethylamine

→

title compound

5-Chloro-3-[4-(3-diethylaminopropoxy)benzoyl]-2-phenylbenzofuran

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThe reaction mixture is concentrated under reduced pressure
2. 2
   workup.DISSOLUTIONthe residue is dissolved in ether
3. 3
   WaschenThe ether solution is washed with aqueous sodium hydroxide and water
4. 4
   Einengenthen concentrated

Vorschrift

5-Chloro-3-[4-(3-bromopropoxy)benzoyl]-2-phenylbenzofuran (2.0 g., 4.3 mmol.) is refluxed in 100 ml. of ethanol containing 9 ml. of diethylamine for ten hours. The reaction mixture is concentrated under reduced pressure and the residue is dissolved in ether. The ether solution is washed with aqueous sodium hydroxide and water then concentrated to give the title compound.

Quelle