Reaktion #2485158

ord-dc17b358e011479f8d25c5ea7511f966

Reaktionsgleichung

C[C@]12CC[C@H]3[C@@H](CCC4=CCCC[C@@]43CO)[C@@H]1CC[C@@H]2O
4-androstene-17β,19-diol
C[C@H]1CCC=C2CC[C@H]3[C@@H]4CC[C@H](O)[C@@]4(C)CC[C@@H]3[C@]21CO
1α-methyl-4-androstene-17β,19-diol
→
C[C@]12CC[C@H]3[C@@H](CCC4=CCCC[C@@]43C=O)[C@@H]1CCC2=O
4-androstene-17,19-dione

Edukte

C[C@]12CC[C@H]3[C@@H](CCC4=CCCC[C@@]43CO)[C@@H]1CC[C@@H]2O
4-androstene-17β,19-diol
C[C@H]1CCC=C2CC[C@H]3[C@@H]4CC[C@H](O)[C@@]4(C)CC[C@@H]3[C@]21CO
1α-methyl-4-androstene-17β,19-diol

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

In the same manner, substituting 4-androstene-17β,19-diol for the 1α-methyl-4-androstene-17β,19-diol above results in the preparation of 4-androstene-17,19-dione.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04022769uspto-grants-1977_05