Reaktion #2483579

Reaktionsgleichung

2-amino-1-propanol

ethyl propiolate

→

Ethyl 3-[(1-hydroxyprop-2-yl)amino]acrylate

Lösungsmittel

dimethylformamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturcooled
2. 2
   workup.STIRRINGfurther stirred at room temperature for 2 hour

Vorschrift

3.76 g (50 mmol) of 2-amino-1-propanol (III: R=methyl) was added to 100 ml of dimethylformamide and cooled. To this, 4.91 g (50 mmol) of ethyl propiolate (II, R1 =ethyl) was slowly added dropwise. The reactant mixture was stirred at not more than 5° C. for 6 hours and further stirred at room temperature for 2 hour.

Quelle