Reaktion #2482

Reaktionsgleichung

ethanol

ethyl 3-(N-vinylformamido)propionate

ethylene glycol

sodium methoxide

→

desired product

2-hydroxyethyl 3-(N-vinylformamido)propionate

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturHeating for an additional hour at 135° C.

Vorschrift

The apparatus of Example 2 was charged with 17.1 grams (0.1 mol) of ethyl 3-(N-vinylformamido)propionate, 6.2 grams (0.1 mol) of ethylene glycol, and 0.15 gram of 25% sodium methoxide in methanol solution. The mixture was stirred at 90° C. for 2 hours. No evolution of ethanol was observed during the reaction period. Heating for an additional hour at 135° C. also failed to generate a volatile coproduct which indicated no conversion to the desired product.

Quelle