Reaktion #2477069

Reaktionsgleichung

(2-Ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)acetonitrile

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title compound

Ausbeute 98.3%

2-(2-ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)ethanamine

Ausbeute 98.3%

Lösungsmittel

ammonia methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe catalyst was filtered through celite
2. 2
   Einengenthe filtrate was concentrated under reduced pressure

Vorschrift

(2-Ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)acetonitrile (120 mg, 0.528 mmol) and Raney cobalt (1.2 g) were suspended in 2M ammonia/methanol solution (25 mL), and the suspension was stirred at room temperature for 12 hr under a hydrogen atmosphere. The catalyst was filtered through celite, and the filtrate was concentrated under reduced pressure to give the title compound (120 mg, yield 98%).

Quelle