Reaktion #2469791

Reaktionsgleichung

2-Amino-4-methylpyrimidine

n-bromosuccinimide

→

title compound

5-Bromo-4 methyl-pyrimidin-2-ylamine

Lösungsmittel

CHCl3

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent is removed in vacuo, water
2. 2
   workup.ADDITIONis added
3. 3
   workup.STIRRINGthe mixture is stirred at room temperature for 30 minutes
4. 4
   FiltrationThe resulting precipitate is collected by filtration
5. 5
   Sonstigedried under vacuum oven

Vorschrift

2-Amino-4-methylpyrimidine (10 g, 91.6 mmol), n-bromosuccinimide (17.9 g, 100.8 mmol) and CHCl3 are mixed together and stirred at room temperature for 1 hour. The solvent is removed in vacuo, water is added and the mixture is stirred at room temperature for 30 minutes. The resulting precipitate is collected by filtration and dried under vacuum oven to afford the title compound.

Quelle