Reaktion #2466705

ord-d849200d1f1a4eb3b0e88577e2a46dbb

Reaktionsgleichung

COC(=O)CC(O)CCC=C(C)CCC=C(C)CCC=C(C)C
methyl 3-hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoate
[Na+].[OH-]
sodium hydroxide
→
CC(C)=CCCC(C)=CCCC(C)=CCCC(O)CC(=O)O
title compound
CC(C)=CCCC(C)=CCCC(C)=CCCC(O)CC(=O)O
3-Hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoic acid

Edukte

COC(=O)CC(O)CCC=C(C)CCC=C(C)CCC=C(C)C
methyl 3-hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoate
[Na+].[OH-]
sodium hydroxide

Reagenzien

Keine

Lösungsmittel

CCO
ethanol

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe crude mixture was purified by flash chromatography on a 20 mm ID silica gel column
  2. 2
    WaschenElution of the column with choloform

Vorschrift

A solution of methyl 3-hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoate (139 mg, 430 μmol), ethanol (1 mL) and sodium hydroxide (1N, 440 μL, 440 μmol) was stirred at room temperature for two-hours. The crude mixture was purified by flash chromatography on a 20 mm ID silica gel column. Elution of the column with choloform:acetic acid (40:1/v=v) gave title compound as a colorless gum.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05362906uspto-grants-1994_11