Reaktion #2458616

Reaktionsgleichung

(-)-menthoxyacetic acid

thionyl chloride

→

title compound

Ausbeute 107.4%

(-)-Menthoxyacetyl chloride

Ausbeute 107.4%

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe thionyl chloride is first removed from the solution by distillation under reduced pressure
2. 2
   workup.ADDITION3 ml of dry benzene are then added in order
3. 3
   Sonstigeto remove residual thionyl chloride
4. 4
   workup.DISTILLATIONby means of vacuum distillation

Vorschrift

0.771 g (3.6 mmol) of (-)-menthoxyacetic acid is stirred under reflux with 2.1 g of thionyl chloride for 4 to 5 h. The thionyl chloride is first removed from the solution by distillation under reduced pressure. 3 ml of dry benzene are then added in order to remove residual thionyl chloride by means of vacuum distillation. 0.9 g of the title compound is obtained.

Quelle